Flush free form of niacin
Inositol hexanicotinate (IHN), also known as inositol niacinate, is a flush-free form of niacin without the binders or fillers found in other flush-free, niacin products. The side effects of niacin which may occur at the dosages required for therapeutic efficacy range from flushing and pruritus to hepatoxicity (timed released niacin) and impaired glucose tolerance. By contrast, IHN does not produce these side effects.
Studies have reported significant lipid-lowering effects of IHN at doses of 400 mg, 3-4 times daily. Welsh and Eade found IHN more effective than niacin in its hypocholesterolemic, antihypertensive and lipotropic effects. Like niacin, IHN lowers LDL cholesterol, Lp(a) lipoprotein, triglyceride, and fibrinogen levels while simultaneously raising HDL cholesterol levels.
The mechanisms of action of inositol hexanicotinate are similar to those for niacin. Niacin appears to affect blood lipids by a number of different mechanisms. It lowers LDL and triglyceride levels by decreasing VLDL synthesis, which results in a decrease in the LDL cholesterol fraction. The decrease in VLDL and LDL then leads to a decrease in serum triglycerides, phospholipids and cholesterol, which generally combine with these lipoproteins. Niacin also inhibits cholesterol synthesis from acetate in the liver and increases its degradation. Niacin also reduces coronary artery disease by altering the function of lipoprotein A-I and reducing synthesis of lipoprotein A-II. This appears to result in an elevation of HDL levels.

Recommended dosage:
One capsule per day.

Product Specifications:
Serving Size: 1 Capsule
Amount Per Serving	% Daily Value
Niacin	500mg		2,500%
(vitamin B-3 as inositol hexanicotinate)
Inositol (inositol hexanicotinate)	125mg		*
*Daily Value not established
Other Ingredients: Hydroxypropylmethylcellulose (Vcap) and magnesium stearate. Contains no added sugar, starch, salt, wheat, gluten, corn, coloring, dairy products, flavoring, or preservatives. Keep container tightly closed in a cool, dry and dark place. Keep out of reach of children.

Quantity:	Price: £16.33