Additional support to block harmful AGE's
Benfotiamine (technically known as s-benzoylthiamine-o-monophosphate) is a synthetic fat-soluble form of thiamine (vitamin B1). It is highly effective at increasing plasma and cellular levels of thiamine diphosphate (TDP). TDP is the metabolically active coenzyme form of B1. Human, animal and cell studies show that benfotiamine reduces formation of advanced glycosylation end products. (AGEs) that crosslink body proteins such as collagen, rendering them structurally and functionally ineffective. AGEs increase with high blood sugar and aging, and are involved in the pathogenesis of many of the diseases of aging, including atherosclerosis, arthritis, and cataracts.
AGEs especially attack long-lived proteins such as collagen, the most abundant protein in the body, which makes up a significant part of skin, bones, cartilage, tendons, teeth and the cardiovascular system. AGEs cross-link various proteins, making them stiffer and less elastic. They damage normal three-dimensional protein structure, inhibit the physiologic function of proteins, and trigger inflammatory reactions. These stable compounds [AGEs] accumulate slowly throughout the lifespan and contribute to structural and physiologic changes in the cardiovascular system such as increased vascular and myocardial stiffness, endothelial dysfunction, altered vascular injury responses, and atherosclerotic plaque formation. Quite literally, AGEs are a major causal contributor to aging and the diseases of aging. And unfortunately, there are no enzymes in the body able to break down these AGEs and their pathologic and unwanted cross-links to proteins.
Over the past decade researchers have discovered that benfotiamine has been shown to be an AGE-blocker both in vitro (“test tube”) and in vivo (living animals).
Dosage:
1 capsule 2 or 3 times per day
| Product Specifications: |
| Serving Size:1 Capsule |
| Amount Per Serving | % Daily Value |
| |
| Thiamin (vitamin B1 from 150 mg benfotiamine | 100mg | | 6,933% |
| (S-benzyolthiamine-O-monophosphate) |
| *Daily Value not established |
Other Ingredients: Hydroxypropyl methylcellulose (Vcap), and microcrystalline cellulose. Contains no added sugar, starch, salt, wheat, gluten, corn, coloring, dairy products, flavoring, or preservatives. Keep container tightly closed in a cool, dry and dark place. Keep out of reach of children. |